Cancer-Derived Transforming Growth Factor-β Modulates Tumor-Associated Macrophages in Ampullary Cancer.

Li-Chin Cheng Ying-Jui Chao Chih-Yang WangNam Nhut PhanYi-Ling ChenTzu-Wen WangHui-Ping Hsu Yih-Jyh LinYan-Shen ShanMing-Derg Lai

Published in: OncoTargets and therapy (2020)

The present study demonstrates that TGF-β modulates macrophage activity in ampullary cancer. Targeting TGF-β could be an approach to activating immunosurveillance.

Keyphrases

transforming growth factor
papillary thyroid
epithelial mesenchymal transition
squamous cell
signaling pathway
squamous cell carcinoma
cancer therapy