Treatment of Concurrent Depression and Its Effect on Outcomes After Total Joint Arthroplasty: A Systematic Review of Comparative Studies.

Samuel B MorganAli ShahabiColin KruseMichael ZywielJesse WolfstadtSeper Ekhtiari

Published in: The Journal of the American Academy of Orthopaedic Surgeons (2023)

Interventions targeted at PDDs may improve short-term pain and functional outcomes, and there may be an association between selective serotonin reuptake inhibitor use and implant survival. The current literature is limited and inconclusive, with important gaps in understanding regarding the optimization and treatment of this modifiable risk factor. Surgeons should consider depression treatment as a method to improve outcomes in this cohort.

Keyphrases

systematic review
depressive symptoms
risk factors
metabolic syndrome
radiation therapy
sleep quality
rectal cancer
glycemic control
case control
postoperative pain