Identification of a Novel Ferroptosis-Related Gene Signature for Predicting Prognosis and Responsiveness to Immunotherapy in Hepatocellular Carcinoma.

Qingbin WangBingkun WangXiaowu MaHongkai ZhuangZhiqin XieChenwei TangWenliang TanLei YangChangzhen ShangYajin Chen

Published in: Journal of hepatocellular carcinoma (2023)

We developed a prognostic signature based on FRGs to predict OS of HCC patients. And the signature may facilitate clinicians in identifying those who are likely to benefit from ICIs. The results also indicated that ZFP69B might regulate the process of ferroptosis and could be used as a novel potential target for HCC.

Keyphrases

end stage renal disease
cell death
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
gene expression
risk assessment
bioinformatics analysis