Non-canonical EphA2 activation underpins PTEN-mediated metastatic migration and poor clinical outcome in prostate cancer.
Ashwin SachdevaClaire A HartKyungmin KimThomas TawadrosPedro OliveiraJonathan ShanksMichael D BrownNoel ClarkePublished in: British journal of cancer (2022)
EphA2 MAT-related signalling confers transendothelial invasion. This is associated with a substantially worse prognosis in PTEN-deficient PCa.