Impact of Naples Prognostic Score at Admission on In-Hospital and Follow-Up Outcomes Among Patients with ST-Segment Elevation Myocardial Infarction.
Aslan ErdoğanÖmer GençEyüp OzkanMuhammed M GoksuErsin IbisogluMehmet N BilenAhmet GulerAli KaragözPublished in: Angiology (2023)
The Naples prognostic score (NPS) consists of cholesterol level, albumin concentration, lymphocyte-to-monocyte and neutrophil-to-lymphocyte ratios and reflects systemic inflammation, malnutrition, and survival for various conditions. We investigated the relationship of NPS at admission with in-hospital and follow-up outcomes among ST-segment elevation myocardial infarction (STEMI) patients. This retrospective study included 1887 consecutive patients diagnosed with STEMI and who underwent primary percutaneous coronary intervention between March 2020 and May 2022. The study population was divided by NPS into 2; low (0-1-2) and high (3-4). In-hospital adverse events and all-cause mortality rates during follow-up were extracted from the registry. The Median follow-up time was 15 months. The overall mortality rate was 14.6%. The proportions of in-hospital events that included acute respiratory failure, acute kidney injury, malignant arrhythmia, and mortality were significantly higher in the high NPS group than in the low NPS group. Compared with the baseline model, in the full model of Cox regression analysis; NPS was an independent predictor of all-cause mortality (adjusted hazard ratio (aHR): 2.49, 95%CI, 1.75-3.50, P < .001), with a significant improvement in model performance (likelihood ratio χ 2 , P < .001) and better calibration. In conclusion, we found an association between NPS and in-hospital and follow-up outcomes in STEMI patients.
Keyphrases
- st segment elevation myocardial infarction
- percutaneous coronary intervention
- end stage renal disease
- ejection fraction
- healthcare
- acute kidney injury
- newly diagnosed
- st elevation myocardial infarction
- acute coronary syndrome
- respiratory failure
- acute myocardial infarction
- coronary artery disease
- emergency department
- prognostic factors
- antiplatelet therapy
- coronary artery bypass grafting
- peritoneal dialysis
- cardiovascular disease
- acute care
- adipose tissue
- risk factors
- type diabetes
- extracorporeal membrane oxygenation
- cardiac surgery
- cardiovascular events
- immune response
- drug induced
- acute respiratory distress syndrome
- glycemic control