MDA5-autoimmunity and Interstitial Pneumonitis Contemporaneous with the COVID-19 Pandemic (MIP-C).

Khizer IqbalSaptarshi SinhaPaula DavidGabriele De MarcoSahar TaheriElla McLarenSheetal MaisuriaGururaj ArumugakaniZoe AshCatrin BuckleyLauren ColesChamila HettiarachchiGayle SmithsonMaria SladeRahul ShahHelena Marzo-OrtegaMansoor KeenCatherine LawsonJoanna MclorinanSharmin NizamHanu ReddyOmer SharifShabina SultanGui TranMark WoodSamuel WoodPradipta GhoshDennis McGonagle

Published in: medRxiv : the preprint server for health sciences (2023)

A distinct pattern of MDA5-autoimmunity cases surged contemporaneously with circulation of the SARS-COV-2 virus during COVID-19. Bioinformatic insights suggest a shared immunopathology with known autoimmune lung disease mechanisms.

Keyphrases

sars cov
breast cancer cells
celiac disease
cell cycle arrest
respiratory syndrome coronavirus
multiple sclerosis
cell death
cell proliferation