Periodontitis activates the NLRP3 inflammasome in serum and saliva.

Gaetano Isola Alessandro Polizzi Simona SantonocitoAngela AlibrandiRay C Williams

Published in: Journal of periodontology (2021)

The results of the present study showed that periodontitis and periodontitis + type-II DM patients had higher serum and salivary NLRP3 concentrations in comparison to healthy controls and patients with type-II DM. Periodontitis was demonstrated to be a significant predictor of both serum and salivary NLRP3 concentrations.

Keyphrases

nlrp inflammasome
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
peritoneal dialysis
patient reported outcomes