Effect of Testosterone on Proliferation Markers and Apoptosis in Breasts of Ovariectomized Rats.

Jussara Celi Conceição OliveiraMarcelo Luis SteinerThérèse Rachell TheodoroAna Maria Amaral Antonio MaderGiuliana PetriLuiz Carlos AbreuMaria Aparecida da Silva PinhalCésar Eduardo FernandesLuciano de Mello Pompei

Published in: Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia (2019)

Isolated T did not have a proliferative effect on the mammary tissue, contrary to EB. Testosterone in combination with EB may or may not decrease the proliferation, depending on the dose of T.

Keyphrases

replacement therapy
signaling pathway
oxidative stress
endoplasmic reticulum stress
cell death
bone loss
cell proliferation