CDCA2 promotes the proliferation of colorectal cancer cells by activating the AKT/CCND1 pathway in vitro and in vivo.
Yifei FengWenwei QianYue ZhangWen PengJie LiQiou GuDongjian JiZhiyuan ZhangQingyuan WangDongsheng ZhangYueming SunPublished in: BMC cancer (2019)
This study demonstrates that overexpression of CDCA2 might target CCND1 to promote CRC cell proliferation and tumorigenesis through activation of the PI3K/AKT pathway.