Effect of medication withdrawal on pain in Parkinson's disease patients - an observational study based on a sample of patients without antiparkinsonian medications.

Rosimary Amorim Lopes José Oswaldo de Oliveira Júnior Fabio Henrique de Gobbi Porto Ricardo Vieira Botelho

Published in: Revista da Associacao Medica Brasileira (1992) (2021)

The interruption of the administration of specific medications in patients with Parkinson's disease caused, or increased the intensity of, painful discomfort correlated with the intensity of functional impairment. This effect was also observed in women, but it was statistically relevant only for men. The results suggest that pain may be a "red flag" that points to the need for a therapeutic drug review when its presence or worsening is detected.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic pain
chronic kidney disease
prognostic factors
emergency department
pain management
type diabetes
metabolic syndrome
high intensity
pregnant women
spinal cord
patient reported
insulin resistance
skeletal muscle
adverse drug
electronic health record