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Practice Effects of Mobile Tests of Cognition, Dexterity, and Mobility on Patients With Multiple Sclerosis: Data Analysis of a Smartphone-Based Observational Study.

Tim WoelfleSilvan PlessAndrea WiencierzLudwig KapposYvonne NaegelinJohannes Lorscheider
Published in: Journal of medical Internet research (2021)
Smartphone-based tests are promising for monitoring the disease trajectories of MS and other chronic neurological diseases. Our findings suggest that strong long-term practice effects in cognitive and dexterity functions have to be accounted for to identify disease-related changes in these domains, especially in the context of personalized health and in studies without a comparator arm. In contrast, changes in mobility may be more easily interpreted because of the absence of long-term practice effects, even though short-term learning effects might have to be considered.
Keyphrases
  • healthcare
  • primary care
  • magnetic resonance
  • multiple sclerosis
  • mass spectrometry
  • ms ms
  • magnetic resonance imaging
  • machine learning
  • computed tomography
  • risk assessment
  • blood brain barrier
  • case control