Antibody Mediated Rejection is not Associated with Worse Survival in Adherent Heart Transplant Patients in the Contemporary Era.
Paul J KimVincenzo CusiAshley CardenasYuko TadaFlorin VaidaNicholas WetterstenJennifer ChakPriyesha BijlaniVictor PretoriusMarcus Anthony UreyGerald P MorrisGrace LinPublished in: medRxiv : the preprint server for health sciences (2023)
Medically adherent C4d+/DSA+ HTx patients show significantly greater risk for cardiac allograft dysfunction but not cardiac mortality or retransplant. In contrast, C4d+/DSA- patients represent a new immunopathologic group with a clinical course similar to that of HTx patients without antibody mediated rejection.
Keyphrases
- end stage renal disease
- chronic kidney disease
- ejection fraction
- newly diagnosed
- peritoneal dialysis
- prognostic factors
- heart failure
- magnetic resonance imaging
- magnetic resonance
- computed tomography
- type diabetes
- patient reported outcomes
- cardiovascular disease
- oxidative stress
- coronary artery disease
- cardiovascular events
- kidney transplantation