Assessment of DNA damages in lymphocytes of agricultural workers exposed to pesticides by comet assay in a cross-sectional study.

Graziana IntranuovoNunzia SchiavulliDomenica CavoneFrancesco BirtoloPierluigi CoccoLuigi VimercatiLinda MacinagrossaAnnamaria GiordanoTommasina PerroneGiuseppe IngravalloPatrizio MazzaMichela StrusiCaterina SpinosaGiorgina SpecchiaGiovanni Maria Ferri

Published in: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals (2018)

The adjusted associations (ORs) between the comet parameters and exposure to pesticides were significant. The sensitivity of the comet test was low (41%), the specificity (89%) and the predictive positive value (0.77) were found acceptable.

Keyphrases

risk assessment
gas chromatography
heavy metals
climate change
circulating tumor
human health
high throughput
physical activity
peripheral blood
risk factors
single molecule
mass spectrometry
nucleic acid
clinical evaluation