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Functional Polymorphisms in IRAKs Are Related to Hepatocellular Carcinoma Risk in Chinese Population.

Hui WangCi SongQi QiTongtong HuangLijuan WangJianguo ChenJian ZhuZhi-Bin HuJuncheng Dai
Published in: BioMed research international (2018)
rs4251545 of IRAK4 (p.Ala428Thr) modified the susceptibility to HBV-related HCC via increased proliferation rate and reduced production of inflammatory cytokines and chemokines. Further well-designed experiments are warranted to validate our findings.
Keyphrases
  • hepatitis b virus
  • signaling pathway