High-Sensitivity Cardiac Troponin I Enhances Preeclampsia Prediction Beyond Maternal Factors and the sFlt-1/PlGF Ratio.
Lucas BacmeisterAlina GoßlingAnnette BuellesbachAnna BirukovJenny E MyersS T ThomasS LeeMarianne Skovsager AndersenJ S JorgensenA DiemertSandra M BloisPetra Clara ArckKurt HecherFlorian HerseStefan BlankenbergRalf DechendDirk WestermannT ZellerPublished in: Circulation (2023)
These exploratory findings uncover a potential role for hs-cTnI as a complementary biomarker in the prediction of preeclampsia. After validation in prospective studies, hs-cTnI, alongside maternal factors, may either be considered as a substitute for angiogenic biomarkers in health care systems where they are sparce or unavailable, or as an enhancement to established prediction models using angiogenic markers.