Zinc oxide nanoparticles and spironolactone-enhanced Nrf2/HO-1 pathway and inhibited Wnt/β-catenin pathway in adenine-induced nephrotoxicity in rats.

Amira AwadallaEman T HamamFardous F El-SendunyNisreen Mansour OmarMohamed R MahdiNashwa BarakatOmar A AmmarAbdelaziz M HusseinAhmed A ShokeirSalma M Khirallah

Published in: Redox report : communications in free radical research (2022)

The therapeutic role of SPL was enhanced by the antioxidant and the anti-inflammatory role of ZnO-NPs, which presented a great renoprotective effect against CKD.

Keyphrases

oxide nanoparticles
anti inflammatory
oxidative stress
diabetic rats
drug induced
stem cells
high glucose
cell proliferation
reduced graphene oxide
visible light