Tweedle gene family of Drosophila suzukii (Matsumura) larva enhances the basal tolerance to cold and hypoxia.

Hypoxia could influence the effect of cold treatment on the survival of D. suzukii positively or negatively. Structural constituent of chitin-based cuticle, especially Twdl genes, body morphogenesis, and ATP synthesis coupled proton transport were involved in the tolerance of cold and hypoxia. In the future, Twdl gene could be used as nanocarrier-delivered RNA pesticides to control D. suzukii in the field to prevent its worldwide spread. This article is protected by copyright. All rights reserved.