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Concordance between Immunohistochemistry and Microarray Gene Expression Profiling for Estrogen Receptor, Progesterone Receptor, and HER2 Receptor Statuses in Breast Cancer Patients in Lebanon.

Ghina B FakhriReem S AkelMaya K KhalilDeborah A MukherjiFouad I BoulosArafat Hussein Tfayli
Published in: International journal of breast cancer (2018)
Our results are in line with the available evidence with the concordance rate being the lowest for the progesterone receptor. In general, microarray gene expression and IHC proved to have high concordance rates. Several factors can increase the discordance rate such as differences in sample processing.
Keyphrases
  • estrogen receptor
  • gene expression
  • dna methylation
  • binding protein