Subclinical First Trimester Renal Abnormalities Are Associated With Preeclampsia in Normoalbuminuric Women With Type 1 Diabetes.

Clare B KellyMichelle B HookhamJeremy Y YuAlicia J JenkinsAlison J NankervisKristian F HanssenSatish K GargJames A ScardoSamar M HammadM Kathryn MenardChristopher E AstonTimothy J Lyons

Published in: Diabetes care (2017)

Early tubular and glomerular dysfunction may predict PE in first trimester women with T1DM, even if free of microalbuminuria. These data suggest that subclinical renal tubular and glomerular injury, if present early in pregnancy, may predispose women with T1DM to PE.

Keyphrases

high glucose
pregnancy outcomes
endothelial cells
diabetic nephropathy
polycystic ovary syndrome
electronic health record
early onset
preterm birth
type diabetes
pregnant women
glycemic control
skeletal muscle
big data
insulin resistance
data analysis
breast cancer risk