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A phase II study of cabozantinib and pembrolizumab in advanced gastric/gastroesophageal adenocarcinomas resistant or refractory to immune checkpoint inhibitors.

Farshid DayyaniJoseph ChaoFa-Chyi LeeThomas H TaylorKristen NeumannMay T Cho
Published in: The oncologist (2024)
The addition of cabozantinib to pembrolizumab shows clinical benefit in ICI-resistant or refractory mGEA with a tolerable safety profile. (ClinicalTrials.gov Identifier: NCT04164979. IRB Approved: UCI 18-124, University of California Irvine IRB#20195426.).
Keyphrases
  • phase ii study
  • advanced non small cell lung cancer
  • open label
  • locally advanced
  • metastatic renal cell carcinoma
  • squamous cell carcinoma
  • radiation therapy
  • tyrosine kinase