Discovery of a pyrano[2,3-b]pyridine derivative YX-2102 as a cannabinoid receptor 2 agonist for alleviating lung fibrosis.
Tao LiuJing GuYi YuanQunfang YangPeng-Fei ZhengChangyu ShanFangqin WangHongwei LiXiang-Qun XieXiao-Hong ChenQin OuyangPublished in: Journal of translational medicine (2022)
These findings suggest that CB2R is a potential target for PF treatment and YX-2102 is a promising CB2R agonist with new chemical space.