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microRNA-199a-5p regulates epithelial-to-mesenchymal transition in diabetic cataract by targeting SP1 gene.

Xin LiuQiaoyun GongLongfei YangMin LiuLingzhi NiuLufei Wang
Published in: Molecular medicine (Cambridge, Mass.) (2020)
Our findings implied miR-199a could be a therapeutic target by regulating SP1 directly to affect EMT in diabetic cataract and provided novel insights into the pathogenesis of diabetic cataract.
Keyphrases
  • type diabetes
  • wound healing
  • long non coding rna
  • epithelial mesenchymal transition
  • genome wide
  • cataract surgery
  • gene expression
  • dna methylation
  • signaling pathway