miR-129-5p Inhibits Adipogenesis through Autophagy and May Be a Potential Biomarker for Obesity.

Xue FuLina JinLuyu HanYini YuanQian MuHui WangJian YangGuang NingDonglei Zhou Zhiguo Zhang

Published in: International journal of endocrinology (2019)

miR-129-5p might target on the ATG7-related autophagy signaling network that regulates white and brown adipogenesis. Importantly, the aforementioned results suggest serum miR-129-5p might be a potential biomarker and therapeutic target for obesity.

Keyphrases

high fat diet induced
insulin resistance
cell death
metabolic syndrome
weight loss
endoplasmic reticulum stress
type diabetes
signaling pathway
weight gain
oxidative stress
adipose tissue
physical activity