Associations between hemispheric asymmetry and schizophrenia-related risk genes in people with schizophrenia and people at a genetic high risk of schizophrenia.
Yue ZhuShuai WangXiaohong GongElliot K EdmistonSuyu ZhongChao LiPengfei ZhaoShengnan WeiXiaowei JiangYue QinJujiao KangYi WangQikun SunGaolang GongFei WangYanqing TangPublished in: The British journal of psychiatry : the journal of mental science (2022)
The shared asymmetric deficits in people with schizophrenia and those with GHR, and the association between anomalous asymmetry and SZ-PRSs suggested a vulnerability imaging marker regulated by schizophrenia-related risk genes. Our findings provide new insights into asymmetry regulated by risk genes and provides a better understanding of the genetic-neural pathological underpinnings of schizophrenia.