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Associations between hemispheric asymmetry and schizophrenia-related risk genes in people with schizophrenia and people at a genetic high risk of schizophrenia.

Yue ZhuShuai WangXiaohong GongElliot K EdmistonSuyu ZhongChao LiPengfei ZhaoShengnan WeiXiaowei JiangYue QinJujiao KangYi WangQikun SunGaolang GongFei WangYanqing Tang
Published in: The British journal of psychiatry : the journal of mental science (2022)
The shared asymmetric deficits in people with schizophrenia and those with GHR, and the association between anomalous asymmetry and SZ-PRSs suggested a vulnerability imaging marker regulated by schizophrenia-related risk genes. Our findings provide new insights into asymmetry regulated by risk genes and provides a better understanding of the genetic-neural pathological underpinnings of schizophrenia.
Keyphrases
  • bipolar disorder
  • genome wide
  • high resolution
  • traumatic brain injury
  • dna methylation
  • climate change
  • copy number
  • transcription factor
  • genome wide analysis