Pre-existing liver disease is associated with poor outcome in patients with SARS CoV2 infection; The APCOLIS Study (APASL COVID-19 Liver Injury Spectrum Study).
Shiv Kumar SarinAshok ChoudhuryGeorge K LauMing-Hua ZhengDong JiSherief Abd-ElsalamJaeseok HwangXiaolong QiIan Homer CuaJeong Ill SuhJun Gi ParkOpass PutcharoenApichat KaewdechTeerha PiratvisuthSombat TreeprasertsukSooyoung ParkSalisa WejnaruemarnDiana A PayawalOidov BaatarkhuuSang Hoon AhnChang Dong YeoUzziel Romar AlonzoTserendorj ChinbayarImelda M LohoOsamu YokosukaWasim JafriSoeksiam TanLau Ing SooTawesak TanwandeeRino GaniLovkesh AnandEslam Saber EsmailMai KhalafShahinul AlamChun-Yu LinWan-Long ChuangA S SoinHitendra K GargKemal KalistaBadamnachin BatsukhHery Djagat PurnomoVijay Pal DaraPravin RathiMamun Al MahtabAkash ShuklaManoj K SharmaMasao Omatanull nullPublished in: Hepatology international (2020)
SARS-Cov-2 infection causes significant liver injury in CLD patients, decompensating one fifth of cirrhosis, and worsening the clinical status of the already decompensated. The CLD patients with diabetes and obesity are more vulnerable and should be closely monitored.