Inhibition of airway remodeling and inflammatory response by Icariin in asthma.
Lingli HuLulu LiHongying ZhangQiuping LiShan JiangJian QiuLingli HuJingcheng DongPublished in: BMC complementary and alternative medicine (2019)
The fact that ICA can alleviate OVA-induced asthma at least partly through inhibition of ASMC proliferation via MAPK/Erk pathway provides a solid theoretical basis for ICA as a replacement therapy for asthma. These data reveal the underlying reasons of the use of ICA-rich herbs in Traditional Chinese Medicine to achieve good results in treating asthma.