The Specific Gravity-Free Method for the Isolation of Circulating Tumor KRAS Mutant DNA and Exosome in Colorectal Cancer.
Tae Hee LeeEunsook ParkYoung-Gon GohHan Byul LeeWoo Sun RouHyuk Soo EunPublished in: Micromachines (2021)
Our proposed alginate bead using the specific gravity-free method suggests that the screening of mutated ctKRAS DNA and miR-31-5 by liquid biopsy aids in identifying the patients, predicting a primary tumor, and monitoring in the early detection of a tumor.