A new experimental design to study inflammation-related versus non-inflammation-related depression in mice.

Pierre CardinalCamille Monchaux de OliveiraJulie SauvantAline FouryMuriel DarnaudérySylvie VancasselNathalie CastanonLucile Capuron

Published in: Journal of neuroinflammation (2021)

These data validate an experimental design suitable to deeply study the mechanisms underlying inflammation-driven depression comparatively to non-inflammatory depression. This design could help to better understand the pathophysiology of treatment resistant depression.

Keyphrases

oxidative stress
depressive symptoms
sleep quality
adipose tissue
insulin resistance
high fat diet induced