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The effect of intravenous human adipose-derived stem cells (hADSC) on transforming growth factor β1 (TGF-β1), collagen type 1, and kidney histopathological features in the unilateral ureteropelvic junction obstruction model of wistar rats.

Safendra SiregarBambang Sasongko NoegrohoMuhammad Ilhamul Karim
Published in: Turkish journal of urology (2020)
Administration of hADSC therapy reduces TGF-β1 and collagen type 1 levels and then improves the histopathological features in the process of renal fibrosis in the UPJO model.
Keyphrases
  • transforming growth factor
  • epithelial mesenchymal transition
  • wound healing
  • endothelial cells
  • stem cells
  • induced pluripotent stem cells
  • signaling pathway
  • low dose
  • smoking cessation
  • replacement therapy