Pterostilbene restores carbapenem susceptibility in New Delhi metallo-β-lactamase-producing isolates by inhibiting the activity of New Delhi metallo-β-lactamases.

Shui LiuJian ZhangYonglin ZhouNaiyu HuJiyun LiYang WangXiaodi NiuXuming DengJianfeng Wang

Published in: British journal of pharmacology (2019)

These findings indicated that pterostilbene combined with meropenem may offer a new safe and potential "lead compound" for the further development of NDM-1 inhibitors.

Keyphrases

gram negative
multidrug resistant
klebsiella pneumoniae
acinetobacter baumannii
drug resistant
signaling pathway
genetic diversity
human health
cystic fibrosis
pseudomonas aeruginosa