Influence of Protein Carbonylation on Human Adipose Tissue Dysfunction in Obesity and Insulin Resistance.

M Carmen Navarro-RuizM Carmen Soler-VázquezAlberto Díaz-Ruiz Juan Ramón PeinadoAndrea Nieto CalongeJulia Sánchez-CeinosCarmen Tercero-AlcázarJaime López-AlcaláOriol Alberto Rangel-ZuñigaAntonio MembrivesJose Lopez-MirandaMaría M MalagónRocío Guzmán-Ruiz

Published in: Biomedicines (2022)

The adipose tissue carbonylome contributes to understanding the molecular mechanism driving adipocyte dysfunction and identifies possible adipose tissue carbonylated targets in obesity-associated insulin resistance.

Keyphrases

insulin resistance
adipose tissue
high fat diet
high fat diet induced
polycystic ovary syndrome
metabolic syndrome
endothelial cells
skeletal muscle
oxidative stress
genome wide
glycemic control
induced pluripotent stem cells
gene expression
weight loss
small molecule
physical activity