Neutrophil extracellular traps in nasal secretions of patients with stable and exacerbated chronic rhinosinusitis and their contribution to induce chemokine secretion and strengthen the epithelial barrier.
Jae Woong HwangJae Hyung KimHyun Jung KimIn Hak ChoiHye Min HanKi Jung LeeTae Hoon KimSang Hag LeePublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2019)
NETs formation increased in exacerbated CRS, inducing chemokine secretion, strengthening the epithelial barrier, and promoting the neutrophils infiltration. Therefore, the release of NETs in CRS might be beneficial or detrimental to CRS patients.