The Interplay between Age and Viral Status in EBV-Related Nasopharyngeal and HPV-Related Oropharyngeal Carcinoma Patients.

Stefano CavalieriPaolo BossiGabriele InfanteRosalba MiceliNicola Alessandro IacovelliEliana IvaldiLaura Deborah LocatiCristiana BergaminiCarlo ResteghiniImperia NuzzoleseSalvatore AlfieriElena ColomboRossana IngargiolaMarzia FranceschiniGiuseppina CalaresoLisa LicitraEster Orlandi

Published in: Cancers (2022)

Several potential age-related (comorbidities, treatment intensity) and disease-related (stage) confounding factors play a prognostic role with differential impacts on both virus and non-virus-related tumors. In HPV+ oropharyngeal cancer and in EBV+ nasopharyngeal cancer patients, age should be considered as the expression of an array of host- and tumor-related features rather than an independent prognostic factor.

Keyphrases

prognostic factors
epstein barr virus
end stage renal disease
squamous cell carcinoma
diffuse large b cell lymphoma
chronic kidney disease
high grade
sars cov
papillary thyroid
long non coding rna
single cell
binding protein
patient reported outcomes
smoking cessation