Diols as Dienophiles: Bridged Carbocycles via Ruthenium(0)-Catalyzed Transfer Hydrogenative Cycloadditions of Cyclohexadiene or Norbornadiene.

Hiroki SatoKeisuke FukayaBinit Sharma PoudelMichael J Krische

Published in: Angewandte Chemie (International ed. in English) (2017)

Highly exo-selective ruthenium(0) catalyzed transfer hydrogenative cycloadditions of 1,2-diols with cyclohexadiene or norbornadiene are described. Novel bridged bicyclic ring systems are accessible from the diol, α-ketol or 1,2-dione oxidation levels with complete control of diastereoselectivity.

Keyphrases

room temperature
electron transfer
hydrogen peroxide