COTI-2 reactivates mutant p53 and inhibits growth of triple-negative breast cancer cells.
Naoise C SynnottDavid O'ConnellJohn CrownMichael J DuffyPublished in: Breast cancer research and treatment (2019)
We conclude that targeting mutant p53 with COTI-2 is a potential approach for treating p53-mutated TNBC.