The Apparent Genetic Anticipation in PMS2-Associated Lynch Syndrome Families Is Explained by Birth-cohort Effect.
Sanne W Ten BroekeMar Rodríguez-GirondoManon SuerinkStefan AretzInge BernsteinGabriel Capellá MunarChristoph EngelEncarna B Gomez-GarciaLiselot P van HestMagnus von Knebel DoeberitzKristina Lagerstedt-RobinsonTom G W LetteboerPal MollerTheo A van OsMarta PinedaNils RahnerMaran J W Olderode-BerendsJenny von SaloméHans K SchackertLiesbeth SpruijtVerena Steinke-LangeAnja WagnerCarli M J TopsMaartje NielsenPublished in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2019)
This new model for studying genetic anticipation provides a standard for rigorous analysis of families with dominantly inherited cancer predisposition.