Fbxw11 impairs the repopulation capacity of hematopoietic stem/progenitor cells.

Lina WangYongjun PiaoDongyue ZhangWenli FengChenchen WangXiaoxi CuiQian RenXiaofan ZhuGuo-Guang Zheng

Published in: Stem cell research & therapy (2022)

Our data demonstrate that Fbxw11 plays a negative role in the maintenance of HSPCs in vitro and repopulation capacity in vivo. Our data also provide valuable transcriptome references for HSPCs in homeostasis.

Keyphrases

electronic health record
big data
gene expression
single cell
genome wide
data analysis