tRNA-derived fragment 3'tRF-AlaAGC modulates cell chemoresistance and M2 macrophage polarization via binding to TRADD in breast cancer.

Dongping MoXun TangYuyan MaDayu ChenWeiguo XuNing JiangJunyu ZhengFeng Yan

Published in: Journal of translational medicine (2024)

3'tRF-AlaAGC might modulate macrophage polarization via binding to TRADD and increase the effect of M2 on promoting the chemoresistance in BC cells through NF-κb signaling pathway.

Keyphrases

signaling pathway
induced apoptosis
pi k akt
cell cycle arrest
epithelial mesenchymal transition
single cell
oxidative stress
cell therapy
cell proliferation
cancer stem cells
stem cells
cell death
nuclear factor
bone marrow
breast cancer risk