Adverse events reported for Mirena levonorgestrel-releasing intrauterine device in France and impact of media coverage.
Claire LangladeAmandine GouverneurPauline Bosco-LévyAurore GouraudMarie-Christine Pérault-PochatJohana BénéGhada Miremont-SalaméAntoine Parientenull nullPublished in: British journal of clinical pharmacology (2019)
This study highlighted the importance of mediatisation impact on spontaneous reporting with changes concerning amounts of reports, type of reporter, and type of reported AEs. For Mirena, this led to generate signals regarding anxio-depressive and sexual disorders.