COVID-19 in lung transplant patients: A case series.
Geert M VerledenLaurent GodinasNatalie LorentPascal Van BleyenberghLieven DupontMarion DelcroixJonas YserbytChristophe DoomsRobin VosPublished in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons (2020)
Several case reports and small case series have been published on coronavirus disease 2019 infection after solid organ transplantation; however, thus far there are limited data on coronavirus disease 2019 infections in lung transplant patients. In the present single-center case series we discuss 10 lung transplant patients with a documented severe acute respiratory syndrome coronavirus 2 infection, diagnosed with nasopharyngeal swab in 8 and bronchoalveolar lavage in 2. Eight of 10 patients needed hospital admission, of whom 1 was in the intensive care unit. He died after 2 weeks from multiple organ failure. The remaining nine patients recovered. Cell cycle inhibitors were withheld in all patients, whereas the calcineurin inhibitor and corticosteroids were continued at the same dose, with an acceptable outcome.
Keyphrases
- coronavirus disease
- end stage renal disease
- chronic kidney disease
- ejection fraction
- newly diagnosed
- sars cov
- cell cycle
- respiratory syndrome coronavirus
- healthcare
- systematic review
- cell proliferation
- patient reported outcomes
- mesenchymal stem cells
- bone marrow
- artificial intelligence
- electronic health record
- deep learning
- adverse drug