Testing cognitive theories with multivariate pattern analysis of neuroimaging data.
Marius V PeelenPaul E DowningPublished in: Nature human behaviour (2023)
Multivariate pattern analysis (MVPA) has emerged as a powerful method for the analysis of functional magnetic resonance imaging, electroencephalography and magnetoencephalography data. The new approaches to experimental design and hypothesis testing afforded by MVPA have made it possible to address theories that describe cognition at the functional level. Here we review a selection of studies that have used MVPA to test cognitive theories from a range of domains, including perception, attention, memory, navigation, emotion, social cognition and motor control. This broad view reveals properties of MVPA that make it suitable for understanding the 'how' of human cognition, such as the ability to test predictions expressed at the item or event level. It also reveals limitations and points to future directions.
Keyphrases
- data analysis
- magnetic resonance imaging
- mild cognitive impairment
- white matter
- working memory
- electronic health record
- endothelial cells
- big data
- autism spectrum disorder
- healthcare
- mental health
- depressive symptoms
- computed tomography
- current status
- contrast enhanced
- artificial intelligence
- deep learning
- case control
- diffusion weighted imaging