A human model of bilateral pulmonary vein sampling to assess the effects of one-lung ventilation on neutrophil function.
Wendy FunstonMarie-Hélène Ruchaud-SparaganoJonathan ScottJason PowellFaye A H CoolesLauren ShelmerdineCliona McDowellDenis O'LearyKaren L BoothStephen C ClarkSimon J LedinghamAnthony J RostronJohn H DarkA John SimpsonPublished in: PloS one (2022)
The intra-operative, bilateral pulmonary vein sampling model provides unique opportunities to assess biological effects of interventions to one lung, with the other lung acting as an internal control. Single-lung ventilation during CPB had no significant effects on neutrophil function.
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