Plasma protein N-glycome composition associates with postprandial lipaemic response.
Panayiotis LoucaTamara ŠtambukAzra Frkatović-HodžićAna NogalMassimo ManginoSarah E BerryHelena DerišGeorge HadjigeorgiouJonathan WolfMartina VinickiPaul W FranksAna M ValdesTim D SpectorGordan LaucCristina MenniPublished in: BMC medicine (2023)
This study provides a comprehensive overview of the interconnections between plasma protein N-glycosylation and postprandial responses, demonstrating the incremental predictive benefit of N-glycans. We also suggest a considerable proportion of the effect of prediabetes on postprandial triglycerides is mediated by some plasma N-glycans.