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Plasma protein N-glycome composition associates with postprandial lipaemic response.

Panayiotis LoucaTamara ŠtambukAzra Frkatović-HodžićAna NogalMassimo ManginoSarah E BerryHelena DerišGeorge HadjigeorgiouJonathan WolfMartina VinickiPaul W FranksAna M ValdesTim D SpectorGordan LaucCristina Menni
Published in: BMC medicine (2023)
This study provides a comprehensive overview of the interconnections between plasma protein N-glycosylation and postprandial responses, demonstrating the incremental predictive benefit of N-glycans. We also suggest a considerable proportion of the effect of prediabetes on postprandial triglycerides is mediated by some plasma N-glycans.
Keyphrases
  • blood glucose
  • amino acid
  • binding protein
  • cell surface
  • type diabetes
  • skeletal muscle
  • small molecule
  • glycemic control