Inhibition of livin overcomes radioresistance in nasopharyngeal carcinoma cells.

Fei MaXia GuJiang-Qi LiuLi-Hua MoGui YangXiao-Rui GengZhi-Qiang LiuZhi-Gang LiuPing-Chang Yang

Published in: PloS one (2020)

Livin expression in NPC cells plays a critical role in the development of radioresistance. Depletion of livin increases the sensitiveness of NPC cells to irradiation. Target therapy against livin may have the translational potential for the treatment of NPC.

Keyphrases

induced apoptosis
cell cycle arrest
endoplasmic reticulum stress
oxidative stress
risk assessment
binding protein
combination therapy