An in vivo model of postinflammatory hyperpigmentation and erythema: clinical, colorimetric and molecular characteristics.

Gautham VellaichamyI KohliRaheel ZubairC YinT BraunbergerA F NahhasC NicholsonTasneem F MohammadP IsedehA B LyonsN NartkerM Al-JamalM MatsuiN Karaman-JurukovskaL ZhouH W LimQ-S MiIltefat H Hamzavi

Published in: The British journal of dermatology (2021)

Our TCA-based in vivo model, using TCA concentrations between 20% and 30% with an optimum of 30%, enables the quantitative assessment of the pigmentary response to varying degrees of cutaneous inflammation in a fashion that mirrors natural acne-induced PIH and PIE.

Keyphrases

oxidative stress
gold nanoparticles
high glucose
diabetic rats
sensitive detection
fluorescent probe
single molecule
quantum dots
hidradenitis suppurativa