Antibacterial Properties of Bilayer Biomimetic Nano-ZnO for Dental Implants.
Xiaheng WangHouyou FanFeng ZhangSiyu ZhaoYuxiao LiuYingying XuRunfa WuDongfang LiYang YangLan LiaoHongshui ZhuXiaolei WangPublished in: ACS biomaterials science & engineering (2020)
Dental implant surgery has a relatively high incidence of peri-implantitis. In this research, ZnO nanorods and ZnO nanospheres were synthesized by a hydrothermal method. ZnO nanorods first covered the surface of Ti or Ti-Zr, and ZnO nanospheres were then modified as the outermost layer. By these means a dual antibacterial effect could be realized by the rapid release of ZnO nanospheres and the sustained release of ZnO nanorods. Subsequent studies implied that this ZnO nanorods-nanospheres hierarchical structure (NRS) could be stably loaded on the surface of roughened Ti and Ti-Zr slices. The modified materials not only showed excellent antibacterial activities against both Escherichia coli and Staphylococcus aureus but also showed low cellular cytotoxicity. This ZnO NRS structure is thus expected to be used as a general antimicrobial coating on the surface of Ti (Ti-Zr) in dental implant surgery.
Keyphrases
- reduced graphene oxide
- room temperature
- quantum dots
- visible light
- staphylococcus aureus
- escherichia coli
- gold nanoparticles
- minimally invasive
- risk factors
- light emitting
- pet imaging
- ionic liquid
- multidrug resistant
- anti inflammatory
- percutaneous coronary intervention
- surgical site infection
- positron emission tomography
- bone regeneration
- anaerobic digestion