Coenzyme Q10 supplementation and oxidative stress parameters: a systematic review and meta-analysis of clinical trials.

Abolfazl AkbariGholam Reza MobiniShahram AgahMojgan MorvaridzadehAmirhossein OmidiEric PotterSiavash FazelianSeyed Hossein ArdehaliElnaz DaneshzadSadegh Dehghani

Published in: European journal of clinical pharmacology (2020)

CoQ10 supplementation, in the tested range of doses, was shown to reduce MDA concentrations, and increase TAC and antioxidant defense system enzymes. However, there were no significant effects of CoQ10 on NO, GSH concentrations, or CAT activity.

Keyphrases

oxidative stress
clinical trial
dna damage
breast cancer cells
induced apoptosis
fluorescent probe
innate immune
heat shock