TRAIL and EGFR Pathways Targeting MicroRNAs are Predominantly Regulated in Human Diabetic Nephropathy.

In silico analysis showed that miRs targeting TRAIL and EGFR signaling are predominately regulated in uEVs and renal tissue of DN subjects. After wet-lab validation, the identified miRs- target pairs may be explored for their diagnostic and/or therapeutic potential in diabetic nephropathy.