Stroke in Pregnancy and Preeclampsia: Effect of Low-Dose Aspirin Treatment on Collateral Flow Velocity and Cerebral Blood Flow Autoregulation During Ischemia in Rats.
Marilyn J CipollaSarah M TremblePublished in: Journal of the American Heart Association (2024)
Low-dose aspirin in ePE reduced infarction that was associated with increased vasodilator prostacyclin and improved collateral perfusion during induced hypertension. The beneficial effect of aspirin on the brain and cerebral circulation is likely multifactorial and worth further study.
Keyphrases
- low dose
- cerebral blood flow
- high dose
- blood pressure
- cerebral ischemia
- pregnancy outcomes
- early onset
- atrial fibrillation
- high glucose
- pulmonary arterial hypertension
- white matter
- diabetic rats
- subarachnoid hemorrhage
- preterm birth
- resting state
- drug induced
- magnetic resonance
- magnetic resonance imaging
- computed tomography
- type diabetes
- contrast enhanced
- endothelial cells
- blood brain barrier
- cardiovascular events