Molecular subclassification of vulvar squamous cell carcinoma: reproducibility and prognostic significance of a novel surgical technique.
Emily F ThompsonLynn HoangAnne Kathrin HöhnAndrea PalicelliKaren L TaliaNairi TchrakianJanine SenzRosebud RusikeSuzanne JordanAmy JamiesonJutta HuvilaJessica N McAlpineC Blake GilksMichael HöckelNaveena SinghLars-Christian HornPublished in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (2022)
Interobserver reproducibility of vulvar squamous cell carcinoma subclassification based on p16 and p53 immunohistochemistry may support routine use in clinical practice. Vulvar field resection surgery showed no significant difference in clinical outcomes when stratified based on HPV status.
Keyphrases
- squamous cell carcinoma
- clinical practice
- sentinel lymph node
- minimally invasive
- locally advanced
- lymph node metastasis
- coronary artery bypass
- high grade
- lymph node
- early stage
- neoadjuvant chemotherapy
- surgical site infection
- single molecule
- coronary artery disease
- acute coronary syndrome
- percutaneous coronary intervention
- cervical cancer screening